ABSTRACT
The pandemic of the COVID-19, has brought a great impact to the education and teaching, so the teaching can only be carried out online, in order to ensure the monitoring and management of teaching quality during teaching. This project import the latest information intelligent teaching system, multi-directional to ensure the monitoring and control of teaching quality, the deep integration of 'Rain Classroom' technology and teaching in this project, So that the interaction information between teachers and students can be recorded in real time during the online teaching, and organized, analyzed, stored also;Import the online teaching platform, collected the students records that finished homework during the epidemic;Import the online virtual experiment platform, online to finished the remote experimental operation of students. Thus, the trinity builds a three-dimensional teaching quality assurance system to escort high-quality big data course teaching during the epidemic. © 2023 IEEE.
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It is important for firms to repurpose production responsively during a crisis such as the COVID-19 pandemic, to seize the market opportunity and create social value. However, occupational health and safety (OHS) can also be a concern in a crisis, and adherence to OHS management systems can undermine a firm's responsiveness in repurposing decision making. We adopt the "capability-rigidity" lens to construct a connection between OHS management standards (i.e., OHSAS 18001) and firms' adaptation responsiveness. After sampling 734 listed Chinese manufacturing firms, our match-based analysis reveals that firms certified with OHSAS 18001 were less responsive during COVID-19 in terms of production repurposing than those without the certification. Yet, certain experience, namely, prepandemic manufacturing of related products, experience of the severe acute respiratory syndrome (SARS) epidemic, and being geographically located close to firms that produced medical supplies, could attenuate this effect. We discuss the implications of our findings in the context of and adding to the literature on safety management, certified management standards, and organizational adaptation and learning.
ABSTRACT
Objective: To provide a basis for the early identification and treatment of severe and critical coronavirus disease 2019 (COVID - 19) by analyzing the clinical characteristics of the death cases. Methods: We retrospectively analyzed the clinical characteristics of 71 COVID - 19 cases which died during hospitalization. The clinical data included general data, underlying disease, clinical manifestation, biochemical laboratory examination, imaging examination, complications, and treatment, then the influencing factors of in - hospital survival were analyzed. Results: Most of the 71 patients were ≥60 years old (78. 9%) and had underlying diseases (74. 6%), in which hypertension ranked first, and fever was the most common first symptom. Biochemical laboratory tests showed that D-Dimer and C-reactive protein maintained at high levels during hospitalization, and lymphocyte count declined. Leukocyte/neutrophil counts, neutrophil to lymphocyte ratio, procalcitonin, creatine kinase, and lactate dehydrogenase increased. The main imaging features of the dead cases were the multifocal ground glass changes and consolidation of the lungs. The most common complications were acute respiratory distress syndrome (89. 9%), shock (34. 3%), and acute myocardial injury (30. 4%). 90% of the patients received auxiliary ventilation, and the decrease of blood oxygen saturation and the increase of procalcitonin may be the risk factors for shorter in-hospital survival. Conclusion: Severe and critical COVID-19 patients show different characteristics in clinical manifestations, biochemical laboratory examination, imaging examination, complications, and treatment reactions, which need early identification and treatment, and bewaring of acute respiratory distress syndrome and multiple organs failure. © 2022 Editorial Board of Medical Journal of Wuhan University. All rights reserved.
ABSTRACT
In this paper, a comprehensive production planning problem under uncertain demand is investigated. The problem intertwines two NP-hard optimization problems: an assembly line balancing problem and a capacitated lot-sizing problem. The problem is modelled as a two-stage stochastic program assuming a risk-averse decision maker. Efficient solution procedures are proposed for tackling the problem. A case study related to mask production is presented. Several insights are provided stemming from the COVID-19 pandemic. Finally, the results of a series of computational tests are reported. (c) 2021 Elsevier B.V. All rights reserved.
ABSTRACT
Since the outbreak of COVID-19, it is becoming important to screen SARS-CoV-2 with high accuracy, high efficiency, and rapidness, for epidemic prevention and control. Conventional detection technologies can not satisfy the requirements of examining massive people in a very short time. Biosensor technology, with the advantages of high sensitivity, good selectivity, low cost, easy miniaturization, and short detection time, is being used to develop real-time detection equipment, thus as a potential alternative for real-time detection of SARS-CoV-2 in clinical diagnosis. In the present study, the authors summarized the construction methods and principles for optical biosensors, electrochemical biosensors, wearable biosensors, magnetic biosensors, gold nanoparticle biosensors, and aptamer biosensors, followed by the introduction of the current application of multiple biosensors in SARS-CoV-2 detection. Conclusively, the technical bottlenecks and future development trends of biosensors in SARS-CoV-2 detection are proposed.
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This paper investigates spatiotemporal dynamics of the effects of urban form on the Covid-19 spread within local communities in Salt Lake County, Utah, in the United States. We identify three types of communities-minority, traditional urban and suburban, and new suburban-and three stages throughout March 2020-September 2021, reflecting the initial, outbreak, and recovery stages. While the traditional urban and suburban communities experience the least risk of Covid-19, minority communities are severely impacted in the initial and outbreak stages, and remote suburban communities are primarily affected in the outbreak and recovery stages. The regression further reveals the role of urban form in the pandemic. High-density urban land use is the main density factor contributing to the disease's spread. In the initial stage, mobility factors such as street connectivity and walkability contribute to the local spread, while land use mixture is the catalyst in the outbreak stage. A comprehensive compact development might offset these negative effects on local public health, and its contribution to local resilience in the recovery stage is also confirmed. Thus, compact development is still valuable for building urban resilience, and proper planning and policies can offset the potential adverse effects of pandemics.
ABSTRACT
Since the outbreak of COVID-19, it is becoming important to screen SARS-CoV-2 with high accuracy, high efficiency, and rapidness, for epidemic prevention and control. Conventional detection technologies can not satisfy the requirements of examining massive people in a very short time. Biosensor technology, with the advantages of high sensitivity, good selectivity, low cost, easy miniaturization, and short detection time, is being used to develop real-time detection equipment, thus as a potential alternative for real-time detection of SARS-CoV-2 in clinical diagnosis. In the present study, the authors summarized the construction methods and principles for optical biosensors, electrochemical biosensors, wearable biosensors, magnetic biosensors, gold nanoparticle biosensors, and aptamer biosensors, followed by the introduction of the current application of multiple biosensors in SARS-CoV-2 detection. Conclusively, the technical bottlenecks and future development trends of biosensors in SARS-CoV-2 detection are proposed. © 2023 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.
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Objective We aimed to review the data available to explore prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection in the real world. Methods We searched observational cohort studies and case-control studies that described the SARS-CoV-2 reinfections in PubMed, Embase, Web of Science, CNKI and WanFang Data from inception to 11 Dec 2022. Studies, data extracted and quality assessed were selected according to strict inclusion exclusion criteria. All analyses were using Stata version 16.0. Results A total of 24 studies were included, involving 78 635 cases of SARS-CoV-2 reinfection and 6 616 869 cases of SARS-CoV-2 primary infection. In cases after the primary SARS-CoV-2 infection, the pooled prevalence of reinfection was 2.06% (95% CI: 1.73% – 2.40%). Compared with other age groups, the secondary infection rate was higher in those aged 40 – < 50 years 2.97% (95% CI: −1. 20%–7 14%) and 50–<60 years 2. 32% (95% CI: –0.74%–5.38%). In vaccination status group, the pooled prevalence was 5.47% (95% CI: 1.99%–8.95%) in unvaccinated cases, 1.85% (95% CI: 1.63%–2.08%) for those received partial COVID-19 vaccination, and 1.11% (95% CI: 0.34%–1.89%) for those received fully vaccination. In addition, the pooled prevalence of SARS-CoV-2 reinfection was 6.02% (95% CI: 5.67%–6. 37%) in the health care workers. Conclusions There is a risk of SARS-CoV-2 reinfection, but the results of this global real-world meta-analysis showed that the rate of reinfection is not high. It is recommended to scientifically understand the risk of SARS-CoV-2 reinfection, strengthen public health education, maintain healthy habits, and reduce the risk of SARS-CoV-2 reinfection. © 2023, Publication Centre of Anhui Medical University. All rights reserved.
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Coronavirus Disease 2019(COVID-19) has shocked the world with its rapid spread and enormous threat to life and has continued up to the present. In this paper, a computer-aided system is proposed to detect infections and predict the disease progression of COVID-19. A high-quality CT scan database labeled with time-stamps and clinicopathologic variables is constructed to provide data support. To our knowledge, it is the only database with time relevance in the community. An object detection model is then trained to annotate infected regions. Using those regions, we detect the infections using a model with semi-supervised-based ensemble learning and predict the disease progression depending on reinforcement learning. We achieve an mAP of 0.92 for object detection. The accuracy for detecting infections is 98.46%, with a sensitivity of 97.68%, a specificity of 99.24%, and an AUC of 0.987. Significantly, the accuracy of predicting disease progression is 90.32% according to the timeline. It is a state-of-the-art result and can be used for clinical usage. © 2022 IEEE.
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Objective: To explore the safety of chloroquine phosphate treatment in patients with novel coronavirus pneumonia (COVID-19) and provide references for clinical safety medication. Method(s): Active monitoring for adverse events (AE) was carried out in the Third People's Hospital of Shenzhen from February to March 2020 during the treatment with chloroquine phosphate in patients with COVID-19. The causal relationship between AE and chloroquine phosphate was evaluated. Result(s): A total of 33 patients were entered in the study, including 16 males and 17 females, aged (43+/-13) years. The clinical types of COVID-19 in 26 patients (78.8%) were mild, in 7 patients (21.2%) were common. There were 7 patients (21.2%) with basic diseases, including 6 with hypertension and 1 with hypothyroidism. The treatment course of chloroquine phosphate was (8+/-3) days. During the treatment, a total of 28 cases of AE in 24 (72.7%) of the 33 patients which were probably or possibly related to chloroquine phosphate were detected. The clinical manifestations of AE included abnormal liver function (8/33, 24.2%), gastrointestinal reactions (8/33, 24.2%), neuropsychiatric system reactions (8/33, 24.2%), cardiovascular system reactions (5/33, 15.2%), eye and vision abnormality (2/33, 6.1%), and skin injury (1/33, 3.0%). The severity of AE was grade 1 or grade 2. After drug withdrawal or symptomatic treatments, all the patients' symptoms were improved and the laboratory tests results returned to normal. Conclusion(s): The adverse effects of chloroquine phosphate in the treatment of patients with COVID-19 are mild, but it is still necessary to strengthen the monitoring.Copyright © 2020 by the Chinese Medical Association.
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The general consensus is that physical activity can prevent and manage lifestyle-induced chronic diseases, and moderate-to-vigorous physical activity (MVPA) has been included in several guidelines of WHO as an indicative intensity standard. Numerous studies have confirmed that improving the spatial quality of urban parks can be very helpful in supporting physical activities, and that the quality of parks is significantly related to the intensity of physical activities. However, few studies have explored the spatial characteristics of activating physical activities. Using a modified System for Observing Play and Recreation in Communities (SOPARC), this study examines the relationship between spatial characteristics and MVPA through a binary logistic regression model. The results reveal that: firstly, inconsistent with other similar studies, the most observed group in the park is the adults rather than the seniors, and the proportion of the females (51%) is higher;secondly, the distribution of MVPA in different groups shows that the seniors have less interaction with other groups, and they have a significant spatial attachment. Thirdly, in functionality, large lawn and jogging trails have been proved to be the most effective features to promote the occurrence of MVPA;among the activity, except for the significant correlation between equipped and MVPA, other attributes can be proved to encourage MVPA as well as those in comfort. In conclusion, our results can contribute to the planning and design of the urban park as well as the further management and allocation of the space and facilities under the vision of promoting public health. © 2023 by the authors.
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In recent years, the corona virus disease 2019 (COVID-19) pandemic has had a huge impact on the global medical, political and economic fields. Since the beginning of the COVID-19 epidemic, our understanding of the impact of COVID-19 has grown exponentially. Recently, the COVID-19 epidemic has changed rapidly in China, and there has been controversy over how to carry out surgical operations for patients with lung neoplastic lesions. Some studies have shown that lung cancer patients undergoing surgery are more likely to experience respiratory failure and perioperative death after contract-ing COVID-19 than the general population, however, delays in cancer treatment are also associated with increased mortality among these patients. In particular, the novel coronavirus Omikron variant has a higher transmissibility and may escape the immunity obtained through the previous novel coronavirus infection and vaccination. In order to minimize the risk of novel coronavirus infection in surgical patients, it is necessary to develop new treatment guidelines, expert consensus and preventive measures. However, the current rapid change of the epidemic situation has led to insufficient time and evidence to develop guidelines and consensus. Therefore, thoracic surgeons need to evaluate specific patient populations at higher risk of severe complications before surgery and weigh the benefit of surgical treatment against the risk of novel coronavirus infection. We try to give some recommendations on lung surgery during the current domestic epidemic situation based on the guidelines and consensus of oncology and thoracic surgery organizations in different regions on lung surgery.Copyright © 2023, Chinese Journal of Lung Cancer. All rights reserved.
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Based on a systematical discussion of the logical relationship between social mentality as a psychological basis of social actions and institutions and social governance, and the online emotion as the core element of the dynamic tendency of internet-based social mentality to form emotional energy to promote the operation of the internet society, this paper conducts an empirical study on the online social mentality and public sentiment guidance during the COVID-19 epidemic in mainland China. We use more than 1 million Weibo dynamic data of 104 accounts of three different types including official media, self-media, and big V media and conduct emotional calculation and judgment to address our objectives. The results show that the public sentiment presented by Weibo as the carrier is mainly positive, among which the official media play a positive role in guiding emotions, while the role played by big Vs' is limited during the COVID-19 epidemic. There exists different public sentiment stemmed from the regional differences brought by the heterogeneity of social governance, economic and social development beyond the media guidance. The study provides valuable internet governance experience on how the government can guide the public to respond to and deal with the crisis with a positive attitude when major public health emergencies occur in the future. © 2022 IEEE.
ABSTRACT
Objective We aimed to review the data available to explore prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection in the real world. Methods We searched observational cohort studies and case-control studies that described the SARS-CoV-2 reinfections in PubMed, Embase, Web of Science, CNKI and WanFang Data from inception to 11 Dec 2022. Studies, data extracted and quality assessed were selected according to strict inclusion exclusion criteria. All analyses were using Stata version 16.0. Results A total of 24 studies were included, involving 78 635 cases of SARS-CoV-2 reinfection and 6 616 869 cases of SARS-CoV-2 primary infection. In cases after the primary SARS-CoV-2 infection, the pooled prevalence of reinfection was 2.06% (95% CI: 1.73% - 2.40%). Compared with other age groups, the secondary infection rate was higher in those aged 40 - < 50 years 2.97% (95% CI: -1. 20%-7 14%) and 50-<60 years 2. 32% (95% CI: -0.74%-5.38%). In vaccination status group, the pooled prevalence was 5.47% (95% CI: 1.99%-8.95%) in unvaccinated cases, 1.85% (95% CI: 1.63%-2.08%) for those received partial COVID-19 vaccination, and 1.11% (95% CI: 0.34%-1.89%) for those received fully vaccination. In addition, the pooled prevalence of SARS-CoV-2 reinfection was 6.02% (95% CI: 5.67%-6. 37%) in the health care workers. Conclusions There is a risk of SARS-CoV-2 reinfection, but the results of this global real-world meta-analysis showed that the rate of reinfection is not high. It is recommended to scientifically understand the risk of SARS-CoV-2 reinfection, strengthen public health education, maintain healthy habits, and reduce the risk of SARS-CoV-2 reinfection.Copyright © 2023, Publication Centre of Anhui Medical University. All rights reserved.
ABSTRACT
Mental stress has been recognized as an essential risk factor for hypertension. Therefore, experts specializing in cardiology, psychiatry, and Traditional Chinese Medicine organized by the Psycho-cardiology Group, College of Cardiovascular Physicians of Chinese Medical Doctor Association, and Hypertension Group of the Chinese Society of Cardiology proposed the expert consensus on the diagnosis and treatment of adult mental stress-induced hypertension in March 2021, which includes the epidemiology, etiology, diagnosis, and treatment of the mental stress-induced hypertension. This consensus will hopefully facilitate the clinical practice of this disorder. In addition, the COVID-19 pandemic has become one of the primary global sources of psychosocial stressors since the beginning of 2020, and the revision of this expert consensus in 2022 has increased the relevant content. This consensus consists of two parts. The sections of Part A include (I) Background and epidemiological characteristics, (II) Pathogenesis, and (III) Diagnosis. The sections of Part B contain (IV) Treatment recommendations, and (V) Prospects. This article presents Part B of the consensus. © 2022 Heart and Mind ;Published by Wolters Kluwer - Medknow.
ABSTRACT
Mental stress has been recognized as an essential risk factor for hypertension. Therefore, experts specializing in cardiology, psychiatry, and Traditional Chinese Medicine organized by the Psycho-Cardiology Group of College of Cardiovascular Physicians of Chinese Medical Doctor Association and Hypertension Group of Chinese Society of Cardiology proposed the expert consensus on the diagnosis and treatment of adult mental stress-induced hypertension in March 2021, which includes the epidemiology, etiology, diagnosis, and treatment of the mental stress-induced hypertension. This consensus will hopefully facilitate the clinical practice of this disorder. In addition, the COVID-19 pandemic has become one of the primary global sources of psychosocial stressors since the beginning of 2020, and the revision of this expert consensus in 2022 has increased the relevant content. This consensus consists of Part A and Part B. Part A includes (I) Background and epidemiological characteristics, (II) Pathogenesis, and (III) Diagnosis and Part B includes (IV) Treatment recommendations and (V) Prospects. This part presents the content of Part A. © 2022 Heart and Mind ;Published by Wolters Kluwer - Medknow.
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Under the dual impact of the deteriorating trend of anti-globalization and the global pandemic of coronavirus, China is facing a severe external economic situation. Facing a period of major change that s rarely seen in a century, the central government has made a strategic decision to speed up a new development pattern of "double circulation”.Under the new international and domestic situation, foreign demand may fluctuate greatly in the future, and the trend of continuous inflow of current account FX may be reversed. The amount of central bank s FX account will also change, which will deeply influence the balance sheet of banks and thus finance and economy. This paper constructs an open macroeconomic DSGE model embedded with base currency, studies the impact of foreign demand shock on economy and finance, puts forward two monetary policy response tools of quantity type and price type linked to import and export gap, and analyzes the relationship between the degree of RMB internationalization and the impact of foreign demand shock. The results show that repairing the bank balance sheet can effectively hedge the credit contraction caused by the decrease of FX, stabilize the financial system and ensure the stable development of economy. © 2021, Tsinghua University Press. All rights reserved.
ABSTRACT
In recent years, the corona virus disease 2019 (COVID-19) pandemic has had a huge impact on the global medical, political and economic fields. Since the beginning of the COVID-19 epidemic, our understanding of the impact of COVID-19 has grown exponentially. Recently, the COVID-19 epidemic has changed rapidly in China, and there has been controversy over how to carry out surgical operations for patients with lung neoplastic lesions. Some studies have shown that lung cancer patients undergoing surgery are more likely to experience respiratory failure and perioperative death after contract-ing COVID-19 than the general population, however, delays in cancer treatment are also associated with increased mortality among these patients. In particular, the novel coronavirus Omikron variant has a higher transmissibility and may escape the immunity obtained through the previous novel coronavirus infection and vaccination. In order to minimize the risk of novel coronavirus infection in surgical patients, it is necessary to develop new treatment guidelines, expert consensus and preventive measures. However, the current rapid change of the epidemic situation has led to insufficient time and evidence to develop guidelines and consensus. Therefore, thoracic surgeons need to evaluate specific patient populations at higher risk of severe complications before surgery and weigh the benefit of surgical treatment against the risk of novel coronavirus infection. We try to give some recommendations on lung surgery during the current domestic epidemic situation based on the guidelines and consensus of oncology and thoracic surgery organizations in different regions on lung surgery.Copyright © 2023, Chinese Journal of Lung Cancer. All rights reserved.